Been Preloading W/ Guar Gum & FOS For One Week and Your Abs Still Don't Shine? Study Shows: It May Take Less Fiber, but More Time for the Anti-Obesity Effects to Show
This is particularly important when we are dealing with rodent studies. While every SuppVersity reader knows that you must not translate the amount of supplements used in rodent studies 1:1 to humans (learn how it works), I must confess that I rarely highlight that the dosages that are used in rodent studies are not the only thing that must not be translated 1:1. The same goes for the time-scale, as well.
You can learn more about the fiber at the SuppVersity
The subjects of the study, male C57BL/6J mice have a lifespan of roughly 750-820 days (max). So, if we assume an average lifespan of 111 weeks for rodents, the 3 week study would be 2.4 years long . in human terms that is (this is a hilariously inaccurate estimate, but I guess it'll serve its purpose).
Figure 1: Changes in adiposity and cumulative food intake over the whole study and during week 1 (Hadri. 2015). |
What appears to be independent of the time-span, though, is the fact that the same amount of fiber in form of alginate would not have any beneficial effects on your body fat levels - just as it didn't do anything for the adipose tissue of the "rodent subjects".
So, if you increase your fiber intake, keep in mind that this is no "quick fix"! Rather than that, it is one of many lifestyle changes the sum of which may help you to control your food intake and limit the storage of body fat.
What the study at hand adds to the existing evidence is thus that (a) it takes patience to see the beneficial effects of fiber pre-loads and that (b) the amount of fiber that's necessary to elicit beneficial effects over the (really) long term may be much lower than the 20g+ previous studies suggested | Comment on Facebook!
References:What the study at hand adds to the existing evidence is thus that (a) it takes patience to see the beneficial effects of fiber pre-loads and that (b) the amount of fiber that's necessary to elicit beneficial effects over the (really) long term may be much lower than the 20g+ previous studies suggested | Comment on Facebook!
- Hadri, Zouheyr, et al. "Long term ingestion of a preload containing fructo-oligosaccharide or guar gum decreases fat mass but not food intake in mice." Physiology & behavior (2015).
- Parnell, Jill A., and Raylene A. Reimer. "Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults." The American journal of clinical nutrition 89.6 (2009): 1751-1759.